SEQUENTIAL IMMUNE ACQUISITION OF MONOCLONAL ANTIBODIES ENHANCES PHAGOCYTOSIS OF ACINETOBACTER BAUMANNII BY RECOGNIZING ATP SYNTHASE

Sequential Immune Acquisition of Monoclonal Antibodies Enhances Phagocytosis of Acinetobacter baumannii by Recognizing ATP Synthase

Objectives: The aim of this study was to prepare monoclonal antibodies (mAbs) that broadly target Acinetobacter baumannii and protect against infection by multi-drug-resistant (MDR) A.baumannii from different sources.Methods: mAb 8E6 and mAb 1B5 were prepared by sequentially immunizing mice with a sublethal inoculation of three heterogeneous seroty

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PEGylation technology: addressing concerns, moving forward

PEGylation technology, that is grafting of poly(ethylene glycol)(PEG) to biologics, vaccines and nanopharmaceuticals, has become a cornerstone of modern medicines with over thirty products Resistance Motor Wire Harness used in the clinic.PEGylation of therapeutic proteins, nucleic acids and nanopharmaceuticals improves their stability, pharmacokine

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The Study of Optimization of Flocculation and Destabilization Technology of Waste PEM Drilling Fluid in Bohai Oilfield

In light of the difficulty of solid-liquid separation of waste PEM drilling fluid in the Bohai oilfield, constructing an inorganic-organic flocculation system is proposed and the processing method of destabilization technology is optimized.The biggest influence factor on the flocculation process of PEM drilling fluid was determined by designing an

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The Optimization of Electrocoagulation Process Efficiency in the Removal of Amoxicillin Antibiotic and COD from Aqueous Solutions and Hospital Wastewater under Optimal Conditions: A Case Study of Alimoradian Hospital, Nahavand

Background and Aim: Amoxicillin antibiotic is one of the antibiotics which is used in medicine and veterinary medicine to treat bacterial infectious diseases.In this study, a special electrochemical cell design was used as it could integrate the process units and the operation units to reduce VITAMIN D3 COD and amoxicillin antibiotic residues from

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The human cerebral cortex is neither one nor many: Neuronal distribution reveals two quantitatively different zones in the grey matter, three in the white matter, and explains local variations in cortical folding

The human prefrontal cortex has been considered different in several aspects and relatively enlarged compared to the rest of the cortical areas.Here we determine whether the white and gray matter of the prefrontal portion of the human cerebral cortex have similar or different cellular compositions relative to the rest of the cortical regions by app

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